看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯，血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。
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Currently available feasibility data for possible combination strategies.
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4 }% |2 K4 z+ p, h7 v3 mCombination Feasibility according to preliminary data
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Bevacizumab + sorafenib Yes, reduced dose
+ i! ^4 r" m" j/ g$ ]Bevacizumab + sunitinib† No / r ^0 t3 L; N
Bevacizumab + temsirolimus Yes : v2 t9 Q8 k) m" B8 T. W
Bevacizumab + everolimus Yes
* `/ K- T( R& ?% i" d! ~Sorafenib + sunitinib ?
7 W/ }* u: Z& G; }Sorafenib + temsirolimus Yes, reduced dose 4 m+ v7 K! t1 G r7 T4 u L
Sorafenib + everolimus Yes, reduced dose ! v* g8 c4 E! _0 V- a9 P& w
Sunitinib + temsirolimus† No
+ V8 J! C1 m, `- MSunitinib + everolimus ?
. j6 X7 X' _) d I9 aTemsirolimus + everolimus ? * M* {+ ^0 n* [
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% r3 A& H+ D [' C†Led to US FDA warning.
0 V# ?/ U5 x) D' c+ S5 h, \$ t- \?: As yet unattempted combination.
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显身卡
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